Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate.

Differentiation therapy may provide an alternative for treatment of cancers that do not respond to cytotoxic chemotherapy or hormonal manipulations. This hypothesis led us to evaluate the effect of a nontoxic differentiation inducer, sodium phenylacetate (NaPA), on hormone-refractory prostate cancer...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Samid, D, Shack, S, Myers, C E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8486788/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116457
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