Cellular HIV-1 DNA Levels in Drug Sensitive Strains Are Equivalent to Those in Drug Resistant Strains in Newly-Diagnosed Patients in Europe

BACKGROUND: HIV-1 genotypic drug resistance is an important threat to the success of antiretroviral therapy and transmitted resistance has reached 9% prevalence in Europe. Studies have demonstrated that HIV-1 DNA load in peripheral blood mononuclear cells (PBMC) have a predictive value for disease p...

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Main Authors: Demetriou, Victoria L., van de Vijver, David A. M. C., Kousiappa, Ioanna, Balotta, Claudia, Clotet, Bonaventura, Grossman, Zehava, Jørgensen, Louise B., Lepej, Snjezana Z., Levy, Itzchak, Nielsen, Claus, Paraskevis, Dimitrios, Poljak, Mario, Roman, Francois, Ruiz, Lidia, Schmidt, Jean-Claude, Vandamme, Anne-Mieke, Van Laethem, Kristel, Vercauteren, Jurgen, Kostrikis, Leondios G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882320/
https://ncbi.nlm.nih.gov/pubmed/20544014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010976
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