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Heme Oxygenase-1 Modulates Mesangial Cell Proliferation by p21(waf1) Upregulation

Mesangial cell (MC) proliferation is a hall mark of many progressive renal diseases. Heme oxygenase-1 (HO-1) has been shown to have an anti-proliferative effect on vascular smooth muscle cells. In the present study, we evaluated the role of HO-1 on MC proliferation and the involved molecular mechani...

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Bibliographische Detailangaben
Hauptverfasser: Kumar, Dileep, Bhaskaran, Madhu, Alagappan, Lakshmi, Tori, Dipti, Yadav, Iti, Konkimala, Sridevi, Magoon, Sandip, Singhal, Pravin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882056/
https://ncbi.nlm.nih.gov/pubmed/20199188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08860220903491240
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