Effects of TLR Agonists on the Hypoxia-Regulated Transcription Factor HIF-1α and Dendritic Cell Maturation under Normoxic Conditions

Dendritic cells (DC) are professional antigen presenting cells that represent an important link between innate and adaptive immunity. Danger signals such as toll-like receptor (TLR) agonists induce maturation of DC leading to a T-cell mediated adaptive immune response. In this study, we show that ex...

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Detalhes bibliográficos
Main Authors: Spirig, Rolf, Djafarzadeh, Siamak, Regueira, Tomas, Shaw, Sidney G., von Garnier, Christophe, Takala, Jukka, Jakob, Stephan M., Rieben, Robert, Lepper, Philipp M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881864/
https://ncbi.nlm.nih.gov/pubmed/20539755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010983
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