Dysregulation of Dopamine Transporters via Dopamine D(2) Autoreceptors Triggers Anomalous Dopamine Efflux Associated with Attention-Deficit Hyperactivity Disorder

The neurotransmitter dopamine (DA) modulates brain circuits involved in attention, reward, and motor activity. Synaptic DA homeostasis is primarily controlled via two presynaptic regulatory mechanisms, DA D(2) receptor (D(2)R)-mediated inhibition of DA synthesis and release, and DA transporter (DAT)...

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Auteurs principaux: Bowton, Erica, Saunders, Christine, Erreger, Kevin, Sakrikar, Dhananjay, Matthies, Heinrich J., Sen, Namita, Jessen, Tammy, Colbran, Roger J., Caron, Marc G., Javitch, Jonathan A., Blakely, Randy D., Galli, Aurelio
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2010
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881830/
https://ncbi.nlm.nih.gov/pubmed/20427663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5094-09.2010
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