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Total Synthesis and Structural Revision of Vannusals A and B. Synthesis of the Originally Assigned Structure of Vannusal B

The total synthesis of the originally assigned structure of vannusal B (2) and its diastereomer (d-2) are described. Initial forays into these structures with model systems revealed the viability of a metathesis-based approach and a SmI(2)-mediated strategy for the key cyclization to forge the centr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nicolaou, K. C., Ortiz, Adrian, Zhang, Hongjun, Dagneau, Philippe, Lanver, Andreas, Jennings, Michael P., Arseniyadis, Stellios, Faraoni, Raffaella, Lizos, Dimitrios E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881636/
https://ncbi.nlm.nih.gov/pubmed/20443561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja100740t
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