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Interaction of Childhood Maltreatment with the Corticotropin-Releasing Hormone Receptor Gene: Effects on HPA Axis Reactivity

BACKGROUND: Variation in the corticotropin-releasing hormone receptor (CRHR1) gene has been shown to interact with early-life stress to predict adult depression. This study was conducted to determine whether CRHR1 polymorphisms interact with childhood maltreatment to predict HPA axis reactivity, whi...

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Autors principals: Tyrka, Audrey R., Price, Lawrence H., Gelernter, Joel, Schepker, Caroline, Anderson, George M., Carpenter, Linda L.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881567/
https://ncbi.nlm.nih.gov/pubmed/19596121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.05.012
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