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Model-based detection of alternative splicing signals

Motivation: Transcripts from ∼95% of human multi-exon genes are subject to alternative splicing (AS). The growing interest in AS is propelled by its prominent contribution to transcriptome and proteome complexity and the role of aberrant AS in numerous diseases. Recent technological advances enable...

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Autors principals: Barash, Yoseph, Blencowe, Benjamin J., Frey, Brendan J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881385/
https://ncbi.nlm.nih.gov/pubmed/20529924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq200
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