Human autoantibodies against the 230-kD bullous pemphigoid antigen (BPAG1) bind only to the intracellular domain of the hemidesmosome, whereas those against the 180-kD bullous pemphigoid antigen (BPAG2) bind along the plasma membrane of the hemidesmosome in normal human and swine skin.

Benzer Materyaller

• The human 230-kD bullous pemphigoid antigen gene (BPAG1). Exon-intron organization and identification of regulatory tissue specific elements in the promoter region.
  Yazar:: Tamai, K, ve diğerleri
  Baskı/Yayın Bilgisi: (1993)
• 92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen.
  Yazar:: Ståhle-Bäckdahl, M, ve diğerleri
  Baskı/Yayın Bilgisi: (1994)
• Unilateral ocular cicatricial pemphigoid with circulating IgA and IgG autoantibodies reactive with the 180 kD bullous pemphigoid antigen.
  Yazar:: Matsuzaki, T, ve diğerleri
  Baskı/Yayın Bilgisi: (1996)
• 180-kD bullous pemphigoid antigen (BP180) is deficient in generalized atrophic benign epidermolysis bullosa.
  Yazar:: Jonkman, M F, ve diğerleri
  Baskı/Yayın Bilgisi: (1995)
• Isolation of a human epidermal cDNA corresponding to the 180-kD autoantigen recognized by bullous pemphigoid and herpes gestationis sera. Immunolocalization of this protein to the hemidesmosome.
  Yazar:: Diaz, L A, ve diğerleri
  Baskı/Yayın Bilgisi: (1990)