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Probing Cellular Traction Forces by Micropillar Arrays: Contribution of Substrate Warping to Pillar Deflection

Quantifying cellular forces relies on accurate calibrations of the sensor stiffness. Neglecting deformations of elastic substrates to which elastic pillars are anchored systematically overestimates the applied forces (up to 40%). A correction factor considering substrate warping is derived analytica...

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Bibliographic Details
Main Authors: Schoen, Ingmar, Hu, Wei, Klotzsch, Enrico, Vogel, Viola
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881340/
https://ncbi.nlm.nih.gov/pubmed/20387859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl100533c
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