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Protacs for Treatment of Cancer
Protein degradation is the cell’s mechanism of eliminating misfolded or unwanted proteins. The pathway by which proteins are degraded occurs through the ubiquitin-proteasome system. Ubiquitin is a small 9-kilodalton (kDa) protein that is attached to proteins. A minimum of four ubiquitins is required...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881331/ https://ncbi.nlm.nih.gov/pubmed/20075761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3181d35017 |
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