Proteinase-activated receptor-2 up-regulation by Fcγ-receptor activation in human neutrophils

We shed new light on the expression and function of the proteinase-activated receptor (PAR) family, associated with inflammation and hyperalgesia, in human granulocytes. Resting cells expressed constitutive levels of PAR-2 and PAR-3 mRNA but not PAR-1 or PAR-4. Based on flow cytometry, stimulation w...

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Detalhes bibliográficos
Main Authors: St-Onge, Mireille, Lagarde, Stéphanie, Laflamme, Cynthia, Rollet-Labelle, Emmanuelle, Marois, Louis, Naccache, Paul H., Pouliot, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881300/
https://ncbi.nlm.nih.gov/pubmed/20154268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-146167
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