A Quantitative Trait Locus (LSq-1) on Mouse Chromosome 7 Is Linked to the Absence of Tissue Loss After Surgical Hindlimb Ischemia

BACKGROUND: Peripheral arterial disease (PAD) caused by occlusive atherosclerosis of the lower extremity has 2 major clinical manifestations. Critical limb ischemia is characterized by rest pain and/or tissue loss and has a ≥40% risk of death and major amputation. Intermittent claudication causes pa...

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Main Authors: Dokun, Ayotunde O., Keum, Sehoon, Hazarika, Surovi, Li, Yongjun, Lamonte, Gregory M., Wheeler, Ferrin, Marchuk, Douglas A., Annex, Brian H.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881228/
https://ncbi.nlm.nih.gov/pubmed/18285563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.107.736447
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