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DNA sequencing by denaturation: experimental proof of concept with an integrated fluidic device
We report the proof of concept of a novel DNA sequencing technology called sequencing by denaturation (SBD). SBD is based on the Sanger sequencing reaction performed on amplified target templates immobilized on a solid surface followed by the denaturation of these Sanger fragments. As these fluoresc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881221/ https://ncbi.nlm.nih.gov/pubmed/20390134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b921417h |
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