Cyclin K and cyclin D1b are oncogenic in myeloma cells

BACKGROUND: Aberrant expression of cyclin D1 is a common feature in multiple myeloma (MM) and always associated with mantle cell lymphoma (MCL). CCND1 gene is alternatively spliced to produce two cyclin D1 mRNA isoforms which are translated in two proteins: cyclin D1a and cyclin D1b. Both isoforms a...

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Autors principals: Marsaud, Véronique, Tchakarska, Guergana, Andrieux, Geoffroy, Liu, Jian-Miao, Dembele, Doulaye, Jost, Bernard, Wdzieczak-Bakala, Joanna, Renoir, Jack-Michel, Sola, Brigitte
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881116/
https://ncbi.nlm.nih.gov/pubmed/20459741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-103
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