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Endocytic pathways mediating oligomeric Aβ42 neurotoxicity
BACKGROUND: One pathological hallmark of Alzheimer's disease (AD) is amyloid plaques, composed primarily of amyloid-β peptide (Aβ). Over-production or diminished clearance of the 42 amino acid form of Aβ (Aβ42) in the brain leads to accumulation of soluble Aβ and plaque formation. Soluble oligo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881055/ https://ncbi.nlm.nih.gov/pubmed/20478062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-19 |
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