Random X Inactivation and Extensive Mosaicism in Human Placenta Revealed by Analysis of Allele-Specific Gene Expression along the X Chromosome

Imprinted inactivation of the paternal X chromosome in marsupials is the primordial mechanism of dosage compensation for X-linked genes between females and males in Therians. In Eutherian mammals, X chromosome inactivation (XCI) evolved into a random process in cells from the embryo proper, where ei...

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Detalhes bibliográficos
Main Authors: Moreira de Mello, Joana Carvalho, de Araújo, Érica Sara Souza, Stabellini, Raquel, Fraga, Ana Maria, de Souza, Jorge Estefano Santana, Sumita, Denilce R., Camargo, Anamaria A., Pereira, Lygia V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881032/
https://ncbi.nlm.nih.gov/pubmed/20532033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010947
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