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A Unified Framework for Detecting Genetic Association with Multiple SNPs in a Candidate Gene or Region: Contrasting Genotype Scores and LD Patterns between Cases and Controls
It is critical to develop and apply powerful statistical tests for genetic association studies due to typically weak associations with complex human diseases or phenotypes. For population-based case-control studies with unphased multilocus genotype data, most of the existing methods are based on com...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
S. Karger AG
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880731/ https://ncbi.nlm.nih.gov/pubmed/19797904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000243149 |
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