Immune complexes from immunized mice and infected cystic fibrosis patients mediate murine and human T cell killing of hybridomas producing protective, opsonic antibody to Pseudomonas aeruginosa.

We examined the basis for the absence in cystic fibrosis (CF) patients of opsonic antibodies to the mucoid exopolysaccharide (MEP) antigen surrounding Pseudomonas aeruginosa that infect these patients. Opsonic antibodies to MEP are found in sera of the minority of CF patients that remain noncolonize...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Pier, G B, Takeda, S, Grout, M, Markham, R B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8450038/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116265
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