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Lowering β-Amyloid Levels Rescues Learning and Memory in a Down Syndrome Mouse Model
β-amyloid levels are elevated in Down syndrome (DS) patients throughout life and are believed to cause Alzheimer's disease (AD) in adult members of this population. However, it is not known if β-amyloid contributes to intellectual disability in younger individuals. We used a γ-secretase inhibit...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880593/ https://ncbi.nlm.nih.gov/pubmed/20532168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010943 |
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