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Lowering β-Amyloid Levels Rescues Learning and Memory in a Down Syndrome Mouse Model
β-amyloid levels are elevated in Down syndrome (DS) patients throughout life and are believed to cause Alzheimer's disease (AD) in adult members of this population. However, it is not known if β-amyloid contributes to intellectual disability in younger individuals. We used a γ-secretase inhibit...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880593/ https://ncbi.nlm.nih.gov/pubmed/20532168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010943 |
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