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Genetic disruption of the autism spectrum disorder risk gene PLAUR induces GABA(A) receptor subunit changes
Disruption of the GABAergic system has been implicated in multiple developmental disorders, including epilepsy, autism spectrum disorder and schizophrenia. The human gene encoding uPAR (PLAUR) has been shown recently to be associated with the risk of autism. The uPAR(-/-) mouse exhibits a regionally...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880553/ https://ncbi.nlm.nih.gov/pubmed/20381588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.03.066 |
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