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Update on the clinical utility of sildenafil in the treatment of pulmonary arterial hypertension

Sildenafil is an orally administered phosphodiesterase type 5 inhibitor that is approved for the treatment of pulmonary arterial hypertension (PAH). The hemodynamic effects of sildenafil are mitigated primarily via potentiating the effects of endogenous nitric oxide, leading to smooth muscle cell re...

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Bibliografiske detaljer
Main Authors: Ramani, Gautam V, Park, Myung H
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880338/
https://ncbi.nlm.nih.gov/pubmed/20531962
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