Variable region expression in the antibody responses of infants vaccinated with Haemophilus influenzae type b polysaccharide-protein conjugates. Description of a new lambda light chain-associated idiotype and the relation between idiotype expression, avidity, and vaccine formulation. The Collaborative Vaccine Study Group.

Haemophilus influenzae b polysaccharide (Hib PS)-protein conjugate vaccines differ chemically and immunologically. To determine whether anti-Hib PS variable region expression might differ according to vaccine formulation, infants were vaccinated at 2, 4, and 6 mo of age with Hib PS coupled to either...

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Pubblicato in:	J Clin Invest
Autori principali:	Granoff, D M, Shackelford, P G, Holmes, S J, Lucas, A H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288029/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8450060/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116298
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