Increased adrenal renin in transgenic hypertensive rats, TGR(mREN2)27, and its regulation by cAMP, angiotensin II, and calcium.

The newly established rat strain TGR(mREN2)27 is a monogenetic model in hypertension research. Microinjecting the mouse Ren-2d renin gene caused it to become a stable part of the genome. The rats are characterized by fulminant hypertension, low plasma active renin, suppressed kidney renin, high plas...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Peters, J, Münter, K, Bader, M, Hackenthal, E, Mullins, J J, Ganten, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288023/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383701/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116292
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