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Gluttony, Sloth and the Metabolic Syndrome: A Roadmap to Lipotoxicity
Once considered divine retribution for sins, comorbidities of obesity (metabolic syndrome) are today attributed to obesity-induced metabolic defects. Here we propose that obesity and hyperleptinemia protect lipid-intolerant nonadipose organs against lipotoxic lipid spillover during sustained caloric...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880185/ https://ncbi.nlm.nih.gov/pubmed/20223680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2010.01.009 |
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