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Lethal mutagenesis and evolutionary epidemiology

The lethal mutagenesis hypothesis states that within-host populations of pathogens can be driven to extinction when the load of deleterious mutations is artificially increased with a mutagen, and becomes too high for the population to be maintained. Although chemical mutagens have been shown to lead...

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Autors principals: Martin, Guillaume, Gandon, Sylvain
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880112/
https://ncbi.nlm.nih.gov/pubmed/20478890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2010.0058
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