Human Liver Expression of CYP2C8: Gender, Age, and Genotype Effects

Research investigating CYP2C8 as a drug-metabolizing enzyme has gained momentum over the past few years. CYP2C8 is estimated to oxidatively metabolize approximately 5% of therapeutically prescribed drugs. It is polymorphically expressed, and several single nucleotide polymorphisms have been identifi...

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Autors principals: Naraharisetti, Suresh Babu, Lin, Yvonne S., Rieder, Mark J., Marciante, Kristin D., Psaty, Bruce M., Thummel, Kenneth E., Totah, Rheem A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2010
Matèries:
Short Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879956/
https://ncbi.nlm.nih.gov/pubmed/20190184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.109.031542
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