Coexpression of phosphotyrosine-containing proteins, platelet-derived growth factor-B, and fibroblast growth factor-1 in situ in synovial tissues of patients with rheumatoid arthritis and Lewis rats with adjuvant or streptococcal cell wall arthritis.

Fibroblast growth factor (FGF)-1 and PDGF-B-like factors have been implicated in the pathobiology of RA and animal models of this disease. Since the receptors for FGF-1 and PDGF are tyrosine kinases, we examined the expression of tyrosine phosphorylated proteins (phosphotyrosine, P-Tyr) in synovial...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Sano, H, Engleka, K, Mathern, P, Hla, T, Crofford, L J, Remmers, E F, Jelsema, C L, Goldmuntz, E, Maciag, T, Wilder, R L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7679410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116235
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