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Estrogen-Dependent and Independent-Mechanisms Contribute to AIB1-Mediated Tumor Formation

We have previously reported the oncogenic properties of the gene ‘Amplified in Breast Cancer 1’ (AIB1), a member of the p160 family of hormone receptor coactivators. In a transgenic mouse model AIB1 overexpression resulted in a high incidence of tumors in various tissues, including mammary gland, ut...

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Hlavní autoři: Torres-Arzayus, Maria I., Zhao, Jin, Bronson, Roderick, Brown, Myles
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879596/
https://ncbi.nlm.nih.gov/pubmed/20442283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4080
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