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Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms

Accumulating evidence suggests that many cancers, including BRCA1- and BRCA2-associated breast cancers, are deficient in DNA repair processes. Both hereditary and sporadic breast cancers have been found to have significant downregulation of repair factors. This has provided opportunities to exploit...

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מידע ביבליוגרפי
Main Authors: Rowe, Bryan P, Glazer, Peter M
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879573/
https://ncbi.nlm.nih.gov/pubmed/20459590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2566
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