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Preparation and topology of the Mediator middle module

Mediator is the central coactivor complex required for regulated transcription by RNA polymerase (Pol) II. Mediator consists of 25 subunits arranged in the head, middle, tail and kinase modules. Structural and functional studies of Mediator are limited by the availability of protocols for the prepar...

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Detalhes bibliográficos
Main Authors: Koschubs, Tobias, Lorenzen, Kristina, Baumli, Sonja, Sandström, Saana, Heck, Albert J. R., Cramer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879511/
https://ncbi.nlm.nih.gov/pubmed/20123732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq029
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