KRAS mutation, KRAS-LCS6 polymorphism, and non-small cell lung cancer

The let-7 family of microRNAs are important regulatory molecules in lung cancer. One downstream target of let-7 is the RAS gene family, including KRAS, an important oncogene in the etiology and clinical outcome of lung adenocarcinoma. Recently, a SNP in the let-7 binding region of the KRAS 3’ UTR wa...

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Bibliographic Details
Main Authors: Nelson, HH, Christensen, BC, Plaza, SL, Wiencke, JK, Marsit, CM, Kelsey, KT
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879467/
https://ncbi.nlm.nih.gov/pubmed/19854534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2009.09.008
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