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Spinal Nerve Ligation in Mouse Upregulates TRPV1 Heat Function in Injured IB4 Positive Nociceptors

Peripheral nerve injury leads to neuropathic pain, but the underlying mechanisms are not clear. The TRPV1 channel expressed by nociceptors is one receptor for noxious heat and inflammatory molecules. Lumbar 4 spinal nerve ligation (SNL) in mice induced persistent heat hyperalgesia 4–10 days followin...

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Main Authors: Vilceanu, Daniel, Honore, Prisca, Hogan, Quinn H., Stucky, Cheryl L.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879455/
https://ncbi.nlm.nih.gov/pubmed/20015699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2009.09.018
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