Intergenic Region 3 of Modified Vaccinia Ankara is a Functional Site for Insert Gene Expression and Allows for Potent Antigen-Specific Immune Responses

Integration of exogenous DNA into modified vaccinia Ankara (MVA) is often accomplished using mapped deletion sites in the viral genome. Since MVA has a large capacity (≥30kb) for foreign gene inserts and a limited number of unique integration sites, development of additional integration sites is nee...

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Detaylı Bibliyografya
Asıl Yazarlar: Manuel, Edwin R., Wang, Zhongde, Li, Zhongqi, La Rosa, Corinna, Zhou, Wendi, Diamond, Don J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879446/
https://ncbi.nlm.nih.gov/pubmed/20471051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.04.015
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