Molecular Basis for the Dual Function of Eps8 on Actin Dynamics: Bundling and Capping

Actin capping and cross-linking proteins regulate the dynamics and architectures of different cellular protrusions. Eps8 is the founding member of a unique family of capping proteins capable of side-binding and bundling actin filaments. However, the structural basis through which Eps8 exerts these f...

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Hauptverfasser: Hertzog, Maud, Milanesi, Francesca, Hazelwood, Larnele, Disanza, Andrea, Liu, HongJun, Perlade, Emilie, Malabarba, Maria Grazia, Pasqualato, Sebastiano, Maiolica, Alessio, Confalonieri, Stefano, Le Clainche, Christophe, Offenhauser, Nina, Block, Jennifer, Rottner, Klemens, Di Fiore, Pier Paolo, Carlier, Marie-France, Volkmann, Niels, Hanein, Dorit, Scita, Giorgio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879411/
https://ncbi.nlm.nih.gov/pubmed/20532239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000387
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