Experimental depletion of CD8(+ )cells in acutely SIVagm-Infected African Green Monkeys results in increased viral replication

BACKGROUND: In vivo CD8(+ )cell depletions in pathogenic SIV infections identified a key role for cellular immunity in controlling viral load (VL) and disease progression. However, similar studies gave discordant results in chronically-infected SMs, leading some authors to propose that in natural ho...

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Autores principales: Gaufin, Thaidra, Ribeiro, Ruy M, Gautam, Rajeev, Dufour, Jason, Mandell, Daniel, Apetrei, Cristian, Pandrea, Ivona
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879233/
https://ncbi.nlm.nih.gov/pubmed/20459829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-42
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