Cardiac Specific, Inducible ClC-3 Gene Deletion Eliminates Native Volume-Sensitive Chloride Channels and Produces Myocardial Hypertrophy in Adult Mice

Native volume-sensitive outwardly rectifying anion channels (VSOACs) play a significant role in cell volume homeostasis in mammalian cells. However, the molecular correlate of VSOACs has been elusive to identify. The short isoform of ClC-3 (sClC-3) is a member of the mammalian ClC gene family and ha...

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Detalhes bibliográficos
Main Authors: Xiong, Dazhi, Heyman, Nathanael S., Airey, Judith, Zhang, Mi, Singer, Cherie A., Rawat, Shanti, Ye, Linda, Evans, Rebecca, Burkin, Dean J., Tian, Honglin, McCloskey, Diana T, Valencik, Maria, Britton, Fiona C., Duan, Dayue, Hume, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879146/
https://ncbi.nlm.nih.gov/pubmed/19615374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.07.003
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