Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration

Ischemia of the heart, brain, and limbs is a leading cause of morbidity and mortality worldwide. Treatment with tissue type plasminogen activator (tPA) can dissolve blood clots and can ameliorate the clinical outcome in ischemic diseases. But the underlying mechanism by which tPA improves ischemic t...

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Detalhes bibliográficos
Main Authors: Ohki, Makiko, Ohki, Yuichi, Ishihara, Makoto, Nishida, Chiemi, Tashiro, Yoshihiko, Akiyama, Haruyo, Komiyama, Hiromitsu, Lund, Leif R., Nitta, Atsumi, Yamada, Kiyofumi, Zhu, Zhenping, Ogawa, Hideoki, Yagita, Hideo, Okumura, Ko, Nakauchi, Hiromitsu, Werb, Zena, Heissig, Beate, Hattori, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879105/
https://ncbi.nlm.nih.gov/pubmed/20110420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-236851
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