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Mucosally delivered peptides prime strong immunity in HLA-A2.1 transgenic rabbits

DNA vaccines delivered subcutaneously by gene-gun have generated strong protective and therapeutic immunity in rabbits. Recent studies have shown that peptides delivered by the mucosal routes also stimulate local and systemic immune responses. Since mucosal delivery is easier to administer and more...

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Bibliographic Details
Main Authors: Hu, Jiafen, Cladel, Nancy, Balogh, Karla, Christensen, Neil
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879011/
https://ncbi.nlm.nih.gov/pubmed/20332046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.03.015
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