The -2518 bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil

Mucosal leishmaniasis (ML) follows localized cutaneous leishmaniasis (CL) caused by Leishmania braziliensis. Proinflammatory responses mediate CL self-healing but are exaggerated in ML. Proinflammatory monocyte chemoattractant protein 1 (MCP-1; encoded by CCL2) is associated with CL. We explore its...

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Bibliografische gegevens
Hoofdauteurs: Ramasawmy, Rajendranath, Menezes, Eliane, Magalhães, Andrea, Oliveira, Joyce, Castellucci, Léa, Almeida, Roque, Rosa, Maria Elisa A., Guimarães, Luiz Henrique, Lessa, Marcus, Noronha, Elza, Wilson, Mary E., Jamieson, Sarra E., Kalil, Jorge, Blackwell, Jenefer M., Carvalho, Edgar M., de Jesus, Amélia Ribeiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878927/
https://ncbi.nlm.nih.gov/pubmed/20430117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2010.04.006
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