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Reducing the Effects of Intracellular Accumulation of Thermolabile Collagen II Mutants By Increasing Their Thermostability in Cell Culture Conditions
Mutations in collagen II are associated with spondyloepiphyseal dysplasia, a group of heritable diseases whose common features include aberrations of skeletal growth. The mechanisms through which mutations in collagen II affect the cartilaginous tissues are complex and include both intracellular and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878901/ https://ncbi.nlm.nih.gov/pubmed/20394730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.04.056 |
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