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Ribosomal protein S19 binds to its own mRNA with reduced affinity in Diamond-Blackfan Anemia

Heterozygous mutations in the ribosomal protein S19 (RPS19) gene are associated with Diamond-Blackfan anemia (DBA). The mechanism by which RPS19 mediates anemia are still unclear, as well as the regulation of RPS19 expression. We show herein that RPS19 binds specifically to the 5′ untranslated regio...

詳細記述

保存先:
書誌詳細
主要な著者: Schuster, Jens, Fröjmark, Anne-Sophie, Nilsson, Per, Badhai, Jitendra, Virtanen, Anders, Dahl, Niklas
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878864/
https://ncbi.nlm.nih.gov/pubmed/20395159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2010.03.007
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