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C-terminal Calmodulin-binding Motif Differentially Controls Human and Rat P2X(7) Receptor Current Facilitation

P2X(7) receptors (P2X(7)R) are ATP-gated calcium-permeable cationic channels structurally unique among the P2X family by their much longer intracellular C-terminal tail. P2X(7)Rs show several unusual biophysical properties, in particular marked facilitation of currents and leftward shift in agonist...

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Detalhes bibliográficos
Main Authors: Roger, Sébastien, Gillet, Ludovic, Baroja-Mazo, Alberto, Surprenant, Annmarie, Pelegrin, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878516/
https://ncbi.nlm.nih.gov/pubmed/20378545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053082
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