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Early activation of invariant natural killer T cells in a rheumatoid arthritis model and application to disease treatment

Invariant NKT (iNKT) cells are a distinctive subtype of CD1d-restricted T cells involved in regulating autoimmunity and capable of producing various T helper type 1 (Th1), Th2 and Th17 cytokines. Activation of iNKT cells by their exogenous ligand α-galactosylceramide (α-GalCer) exerts therapeutic ef...

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Détails bibliographiques
Auteurs principaux: Miellot-Gafsou, Aurore, Biton, Jérôme, Bourgeois, Elvire, Herbelin, André, Boissier, Marie-Christophe, Bessis, Natacha
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878473/
https://ncbi.nlm.nih.gov/pubmed/20113367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03235.x
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