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Effect of mucosal and systemic immunization with virus-like particles of severe acute respiratory syndrome coronavirus in mice

Nasal administration has emerged as a promising and attractive route for vaccination, especially for the prophylaxis of respiratory diseases. Our previous studies have shown that severe acute respiratory syndrome coronavirus (SARS-CoV) virus-like particles (VLPs) can be assembled using a recombinant...

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Detalles Bibliográficos
Main Authors: Lu, Baojing, Huang, Yi, Huang, Li, Li, Bao, Zheng, Zhenhua, Chen, Ze, Chen, Jianjun, Hu, Qinxue, Wang, Hanzhong
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878469/
https://ncbi.nlm.nih.gov/pubmed/20406307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03231.x
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