SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability

SSBP proteins bind and stabilize transcriptional cofactor Lim Domain Binding protein1 (LDB1) from proteosomal degradation to promote tissue specific transcription through an evolutionarily conserved pathway. The human SSBP2 gene was isolated as a candidate tumor suppressor from a critical region of...

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Bibliografiske detaljer
Main Authors: Wang, Yang, Klumpp, Sherry, Amin, Hesham M., Liang, Hong, Li, June, Estrov, Zeev, Zweidler-McKay, Patrick, Brandt, Stephen J., Agulnick, Alan, Nagarajan, Lalitha
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878399/
https://ncbi.nlm.nih.gov/pubmed/20348955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.78
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