CYP17 POLYMORPHISMS AND PROSTATE CANCER OUTCOMES

OBJECTIVE: Cytochrome P450 17α-hydroxylases-C-(17,20)-lyase (CYP17) is a key enzyme involved with the androgen biosynthesis pathway and has recently been targeted for therapy in men with advanced prostate cancer (PCa). However, studies relating prostate cancer outcomes with CYP17 gene variants have...

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Main Authors: Wright, Jonathan L, Kwon, Erika M, Lin, Daniel W, Kolb, Suzanne, Koopmeiners, Joseph S, Feng, Ziding, Ostrander, Elaine A., Stanford, Janet L
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878282/
https://ncbi.nlm.nih.gov/pubmed/20503394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21143
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