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The Presence of a Single N-terminal Histidine Residue Enhances the Fusogenic Properties of a Membranotropic Peptide Derived from Herpes Simplex Virus Type 1 Glycoprotein H

Herpes simplex virus type 1 (HSV-1)-induced membrane fusion remains one of the most elusive mechanisms to be deciphered in viral entry. The structure resolution of glycoprotein gB has revealed the presence of fusogenic domains in this protein and pointed out the key role of gB in the entry mechanism...

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Autors principals: Galdiero, Stefania, Falanga, Annarita, Vitiello, Mariateresa, Raiola, Luca, Russo, Luigi, Pedone, Carlo, Isernia, Carla, Galdiero, Massimiliano
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878091/
https://ncbi.nlm.nih.gov/pubmed/20348105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114819
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