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Foxo3a Regulates Apoptosis by Negatively Targeting miR-21

MicroRNAs are a class of small non-coding RNAs and participate in the regulation of apoptotic program. Although miR-21 is able to inhibit apoptosis, its expression regulation and downstream targets remain to be fully elucidated. Here we report that the transcriptional factor Foxo3a initiates apoptos...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Kun, Li, Pei-Feng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
RNA
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878079/
https://ncbi.nlm.nih.gov/pubmed/20371612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093005
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